Three separate clinical studies each came to the same conclusion: Stannous fluoride containing toothpastes are more effective at controlling mouth odor than are other toothpastes. Most other toothpastes contain sodium fluoride as the active ingredient. A statistically significant greater breath benefit was found with stannous fluoride toothpaste compared to sodium fluoride toothpaste. Stannous fluoride contains tin and has the chemical formula SnF2. It is found in several toothpastes including Colgate Total and Crest Pro Health Gum Protection.