Dentists have been frustrated in the past with the presence of “white spot” lesions on teeth. These lesions are most often seen after orthodontic braces are removed, and are areas of demineralization due to plaque build-up. In the past, we have treated these lesions with fluoride applications in an attempt to remineralize the enamel. These treatments were often met with limited success. Now, a new agent, Casein Phosphoprotein-Amorphous Calcium Phosphate (CPP-AP), had been shown to be more effective at removing these unsightly spots from the teeth. A study at the UT Health Science Center in San Antonio showed that CPP-AP when applied to the tooth surface was much more effective in removing these pesky and unsightly spots than fluoride alone. This is good news for kids who had braces removed only to uncover unsightly white spots.